Optimized Skin Optical Clearing for Optical Coherence Tomography Monitoring of Encapsulated Drug Delivery Through the Hair Follicles

    January 2020 in “ Journal of Biophotonics ”
    Sergey Zaytsev, Yulia I. Svenskaya, Ekaterina V. Lengert … Elina A. Genina
    Studysummary This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.
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    Research cited in this study 7

    1. A Simple Non-Invasive Approach Toward Efficient Transdermal Drug Delivery Based on Biodegradable Particulate System ACS Applied Materials & Interfaces · 2019
    2. Size-Dependent Penetration of Nanoemulsions into Epidermis and Hair Follicles: Implications for Transdermal Delivery and Immunization Oncotarget · 2017
    3. Delivery and Targeting of Nanoparticles into Hair Follicles Therapeutic Delivery · 2014
    4. Drug Delivery to Hair Follicles Expert opinion on drug delivery · 2013
    5. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    6. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010
    7. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004