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research Preliminary investigations of rat skin after topical application of optical clearing agent

1 citations , October 2010 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE”

This study found that while short-term use of PEG-400 and Thiazone affected rat skin structure, the changes were reversible with no long-term effects observed.

research Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles

19 citations , January 2020 in “Journal of Biophotonics”

This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.

research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

2 citations , June 2020 in “Journal of Investigative Dermatology”

This article reviews the steps and methods involved in preparing skin tissues for three-dimensional volumetric imaging, highlighting its potential to provide detailed insights into skin structure not possible with traditional 2D histology, but reports no new findings.

research Formulation and Evaluation of Anti Hair Fall Shampoo of Hibiscus Plant Leaves

April 2026 in “International Journal for Research in Applied Science and Engineering Technology”

In this study, the developed polyherbal shampoo with Hibiscus rosa-sinensis exhibited good stability and cleansing properties, suggesting it may be an effective natural alternative to synthetic anti-hair fall products.

research Developing formulations designed to deliver antiseptic agents to target sites within the skin

September 2019 in “University of Huddersfield Repository (University of Huddersfield)”

In this study, nanoemulsion formulations were found to significantly enhance the skin retention of the antiseptic agent triclosan, with the optimal mixture being a low surfactant concentration, as demonstrated through quantitative and qualitative analysis using tape-stripping and micro CT scans.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Verteporfin and Microneedling

in Treatments 2 years ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

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