Epidermal Growth Factor as a Biological Switch in Hair Growth Cycle

    July 2003 in “ Journal of biological chemistry/˜The œJournal of biological chemistry ”
    Kin Cheung Mak, Sum‐Yin Chan
    Studysummary This study found that continuous expression of epidermal growth factor in transgenic mice prevented hair follicles from entering the catagen phase, implicating EGF as a crucial regulator in hair cycle progression.
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    Research cited in this study 9

    1. Regulation Mechanisms of Hair Growth Current problems in dermatology · 2015
    2. Transforming Growth Factor-Alpha Immunoreactivity During Induced Hair Follicle Growth Cycles in Sheep and Ferrets Journal of histochemistry and cytochemistry/˜The œjournal of histochemistry and cytochemistry · 1996
    3. Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure. The EMBO Journal · 1995
    4. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    5. Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation Cell · 1993
    6. The Secret Life of the Hair Follicle Trends in genetics · 1992
    7. Localization of Epidermal Growth Factor Immunoreactivity in Sheep Skin During Wool Follicle Development Journal of Investigative Dermatology · 1992
    8. Effects of Anti-EGF Serum on Newborn Mice Experientia · 1988
    9. Epidermal Growth Factor Delays Development of Epidermis and Hair Follicles in Mice During First Coat Growth The Anatomical Record · 1983

    Related research 5

    1. Studying Hair Growth Cycle and Its Effects on Mouse Skin Journal of Investigative Dermatology · 2023
    2. Blockade of S100A3 Activity Inhibits Murine Hair Growth Genetics and Molecular Research · 2015
    3. Exogenous Stimulations Change Nude Mouse Hair Cycle Pattern Journal of dermatological treatment · 2010
    4. Treatment of Hair Loss The New England Journal of Medicine · 1999
    5. Effects of Epidermal Growth Factor on Hair Growth in the Mouse Journal of Endocrinology · 1981