Extracellular Proteoglycan Decorin Maintains Human Hair Follicle Stem Cells

    October 2018 in “ The Journal of Dermatology ”
    Katsuma Miyachi, Takaaki Yamada, Mika Kawagishi‐Hotta … Hirohiko Akamatsu
    Studysummary This study suggests that decorin may help maintain hair follicle stem cells and its reduced expression could contribute to age-related hair loss.
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    Research cited in this study 7

    1. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    2. Beta-1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis, and Migration of Their Progeny PLoS ONE · 2013
    3. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    4. The Hair Cycle Journal of Cell Science · 2006
    5. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    6. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    7. Principles of Hair Cycle Control The Journal of Dermatology · 1998

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