20 citations
,
January 2015 in “Current problems in dermatology”
This paper reviews recent research on hair graying, suggesting that an imbalance in oxidative stress handling may affect melanocyte stem cells and melanin production with age, and calls for exploring strategies to prolong melanin production.
15 citations
,
September 2018 in “Hearing research”
This study suggests that rapamycin, but not acarbose, can delay age-relatedloss of cochlear outer hair cells in UM-HET3 mice at doses that increase life span.
November 2025 in “British Journal of Pharmacology”
This study found that inositol hexaphosphate significantly reduced hearing threshold shifts and outer hair cell loss in various sensorineural hearing loss mouse models, suggesting potential for otoprotective use.
13 citations
,
August 2021 in “Frontiers in Aging Neuroscience”
This study found that in SAMP8 mice, phenotypic changes in outer hair cells or the stria vascularis, possibly due to oxidative deficiencies, may predict variability in age-related hearing loss before outer hair cell loss occurs.
Astaxanthin (ASX) is highlighted as a promising supplement for treating hairloss due to its antioxidant properties. It may help with inflammation and oxidative stress, which are linked to hairloss and aging.
A 20-year-old male has been experiencing hairloss since age 15-16 and is using oral minoxidil, dutasteride, and ketoconazole shampoo, with previous use of oral finasteride and topical minoxidil. He has stabilized hairloss but seeks to rule out inflammatory or immune-related causes, considering a scalp biopsy, and is supplementing with vitamin D3, B12, and iron.
Early hairloss causes emotional distress, and common coping strategies like fitness and fashion are inadequate. Treatments like finasteride, minoxidil, dutasteride, hair systems, and scalp micropigmentation were tried but were unsatisfactory.
A 16-year-old considering finasteride for hairloss is advised to consult medical professionals due to age-related concerns, as they are currently using minoxidil and ketoconazole. Users suggest waiting until 17 or consulting a dermatologist for a professional opinion, with some recommending topical finasteride as an alternative.
A woman experienced significant hairloss due to medication, hair coloring, and heat damage, leading her to shave her head and feel distressed. She is considering using wigs and possibly oral minoxidil to manage the situation while her hair regrows.
Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.