Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes

    June 2006 in “ International Journal of Pharmaceutics ”
    Majid Tabbakhian, Naser Tavakoli, Mahmoud Reza Jaafari, Saeid Daneshamouz
    Studysummary This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.
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    Research cited in this study 16

    1. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    2. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    3. Permeant Lipophilicity and Vehicle Composition Influence Accumulation of Dyes in Hair Follicles of Human Skin European journal of pharmaceutical sciences · 2003
    4. Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle Journal of controlled release · 2002
    5. Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro Journal of drug targeting · 2002
    6. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    7. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    8. Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes Journal of Pharmaceutical Sciences · 1997
    9. Topical Finasteride in the Treatment of Androgenic Alopecia: Preliminary Evaluations After a 16-Month Therapy Course Journal of Dermatological Treatment · 1997
    10. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996
    11. The 5 Alpha-Reductase System and Its Inhibitors Dermatology · 1996
    12. Percutaneous Absorption of a New Antiandrogen Included in Liposomes or in Solution International Journal of Pharmaceutics · 1995
    13. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology · 1995
    14. A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1995
    15. Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994
    16. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients With Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994

    Related research 3

    1. Liposomes And Niosomes As Potential Carriers For Dermal Delivery Of Minoxidil Journal of Drug Targeting · 2007
    2. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    3. Influence of Liposomes and Niosomes on the In Vitro Permeation and Skin Retention of Finasteride Iranian Journal of Pharmaceutical Sciences · 2005