Interaction of Polypeptides with Hair in Different Reducing Environments

This study found that novel thiol-reactive cross-linking agents, particularly APA, significantly improved the tensile strength and elasticity of human hair fibers by effectively regenerating disulfide bridges, with potential applications for advanced hair repair treatments in the cosmetic industry.

This study found that using 369LAB Lipid Bond, derived from plant oil triglycerides, can restore lipid content in damaged hair to natural levels and improve hair strength, integrity, and resilience after a single application, with benefits persisting even after discontinuation.

In this study, a bleaching protocol was developed to evaluate hair repair products, revealing that K18® and Olaplex® improve hair brightness and lightness, with distinct impacts on hair fiber properties.

In this study, researchers examined juglone's potential as a restoring agent for hair keratin damaged by permanent or bleaching treatments, finding that juglone formed Michael adducts with cysteine residues, leading to a more regular hair surface as observed via IR spectroscopy and SEM analysis.

This study found that low-molecular-weight hyaluronate significantly improved the mechanical strength and elastic modulus of overbleached hair by enhancing hydrogen bond networks within keratin.

This review discusses the potential of protein-based cosmetics, including keratin-based particles and fusion proteins, to improve hair properties such as strength and shape, but it reports no new clinical results.

This study investigated various proteins as eco-friendly hair perming agents for Asian hair and found that bovine serum albumin and keratin achieved perming results comparable to commercial products, while also increasing hair moisture, indicating a protective effect during heat styling.

This study investigated the effects of wool-derived hydrolysed keratin peptides on relaxed textured hair and found that mid- and high-molecular weight peptides improved mechanical strength and reduced breakage in different humidity conditions.

In this study, researchers evaluated the binding of keratin-associated proteins and α-keratins to human hair fibers, finding that chemical preactivation significantly enhanced binding to natural hair, while perming altered binding characteristics and increased penetration depth.

This study found that pretreatment with KP-Cryst fusion proteins effectively protected Asian and Caucasian virgin hair from thermal damage by maintaining higher water content and preventing structural changes during heat application.

In this study, researchers observed that cosmetic peroxide bleaching causes oxidative damage and protein loss in human hair, not only affecting the cuticle but also deeper cortical structures, correlating with bleaching severity.

This study found that keratin derivatives with functionalized thiol groups improved binding to both natural and bleached hair fibers, suggesting a promising strategy for enhancing keratin's durability in hair repair.

This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.

Keratin peptides can change hair shape gently without harsh chemicals.

This study reviews the biology and cosmetic treatment of hair, emphasizing future advancements in safer, more effective procedures to meet consumer needs for hair care.

This study demonstrated that molecular dynamics simulations of keratin could effectively model the mechanical properties of hair, aligning well with experimental data, especially when conducted in vacuum conditions.

This review considers oxidative stress effects on hair aging and emphasizes the need for dermatologists to recognize and treat factors affecting scalp and hair health, but it provides no new clinical findings.

This review examines hair cosmetics, including shampoos and conditioners, for their formulations and effects, but reports no new clinical findings; it emphasizes the importance of dermatologist knowledge in treating diverse hair conditions.

This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.

This study discusses the proteomic profile associated with hair damage but does not report new experimental findings.

This study found that thioglycolic acid molecules in hair treatments are primarily located in intrafibrillar unordered areas, where they redistribute disulfide bonds.

This study found that a peptide treatment using Protein disulphide isomerase improved the mechanical and thermal properties of over-bleached hair by promoting deeper peptide penetration and attachment.

This review discusses how various factors, including cosmetic procedures and scalp conditions, can damage hair, but highlights the availability of products to improve hair health; it reports no new empirical results.