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20 / 202 resultsresearch Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia
This study highlights a treatment approach using dissolving microneedle patches containing nanomicelles formed by stevioside to enhance the therapeutic efficacy and safety of poorly soluble drugs, as depicted in the cover illustration with luxuriant hair symbolizing its potential effectiveness.
research Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia
This study found that using a stevioside-based microneedle patch significantly increased minoxidil's solubility and skin absorption, promoting hair growth in animal models and achieving 67.5% area coverage by day 35, highlighting the potential of this novel delivery system for androgenetic alopecia treatment.
research Pioneers in Dermatology and Venereology: An Interview with Professor Danilo V. Stevanovic
This autobiographical account details the personal and professional journey of a dermatologist from Yugoslavia, highlighting key influences, career milestones, and reflections on changes in dermatology practice and personal observations over several decades.
research A Mixture of Tocopherol Acetate and L-Menthol Synergistically Promotes Hair Growth in C57BL/6 Mice
In this study, a mixture of tocopherol acetate, L-menthol, and stevioside was more effective in promoting hair growth in mice compared to tocopherol acetate or L-menthol alone.
research Hair Growth Promoting Effect of Toothpaste in C57BL/6 Mice: Active Components and Their Effects on Genomic Expression
This study observed that toothpaste and its active constituents promoted hair growth in mice, suggesting their potential for hair growth applications.
research Human Hair Follicles Can Taste: Stimulation of the Bitter Taste Receptor TAS2R4 Inhibits Hair Growth Ex Vivo by Up-Regulating TGF-β2
This study reports that activating the bitter taste receptor TAS2R4 with rebaudioside A can inhibit hair growth in human scalp hair follicles by promoting catagen through TGF-β pathway activation.
research New Insights Into Human Hair: SAXS, SEM, TEM, and EDX for Alopecia Areata Investigations
This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.
research Incretin-Based Drugs for Obesity: Common and Drug-Specific Reporting Patterns of Adverse Drug Reactions—A Comparative Disproportionality Analysis Using EudraVigilance Reports Integrating SmPC Data
This study analyzed safety data for semaglutide, liraglutide, and tirzepatide from the EudraVigilance database, identifying potential safety signals not listed in current SmPCs, such as optic ischemic neuropathy and pancreatitis, underscoring the importance of ongoing pharmacovigilance.
research Do Alpha-Blockers and 5-Alpha Reductase Inhibitors Increase Dementia Risk? A Network Meta-Analysis
This study examined the dementia risk in patients with benign prostatic hyperplasia using alpha-blockers and 5-alpha reductase inhibitors, finding no significant association between these medications and increased dementia risk compared to no treatment, but noted higher risk probabilities for certain 5ARIs.
research Human CD133+ Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling
This study found that human fetal CD133+ progenitor cells and their conditioned medium accelerated wound healing and promoted angiogenesis in a mouse model of ischemic diabetic ulcers through paracrine mechanisms involving Wnt signaling.
research Current And Prospective Applications Of 3D Printing In Cosmetics: A Literature Review
This review discusses 3D printing developments in topical delivery systems, highlighting the potential for 3D printed microneedles to become prominent in personalized cosmetic applications, but reports no new experimental results.
research Isolation and Molecular Characterization of Malassezia Pachydermatis from a Cutaneous Lesion in a California Sea Lion (Zalophus Californianus)
This study found that Malassezia pachydermatis was present on both lesion and healthy skin in a California sea lion, with significantly more colonies on the lesion site.
research JAK-STAT Pathway-Associated Skin Diseases: A Refined Functional Framework for Inflammatory Skin Diseases
This review highlights the potential for JAK inhibitors to effectively treat inflammatory and autoimmune skin diseases by targeting the JAK-STAT signaling pathway, advocating for an integrated approach to enhance targeted therapy.
research Dupilumab for Prurigo Nodularis: Real-World Outcomes Up to 104 Weeks From the Dupilumab Italian Prurigo Nodularis Study
This study found that treating moderate-to-severe prurigo nodularis with dupilumab significantly improved itch severity, skin condition, and quality of life over 104 weeks, with a favorable safety profile, even in elderly and comorbid patients.
research Clinical Evaluation of a Mesotherapy Formulation for Weakened and Sparse Eyebrows with Assessment of Some Psychological and Social Aspects
This study found that eyebrow mesotherapy with a growth factor-based serum improved eyebrow width, length, density, and psychosocial outcomes such as social engagement, quality of life, confidence, and mood in individuals with sparse or weakened eyebrows.
research 20 Years of the Socioeconomic Impact of Atopic Dermatitis and Alopecia Areata from Around the Globe
This qualitative review reports a high socioeconomic impact of atopic dermatitis and alopecia areata, emphasizing significant quality of life reductions and increased costs, but highlights a lack of comprehensive data from many regions worldwide, underscoring the need for global studies with standardized methodologies.
research Can Hair Be Protected From Oxidative Damage During and After Bleaching
This study assessed three materials—L-arginine, hydrolysed keratin, and cystine-silanol copolymer—ex vivo for their potential to reduce undesirable effects of hair bleaching, such as damage to hair proteins.
research Damage Limitation: Comparing the Impact of Polymers on Bleached Hair, When Applied Within or as Post-Bleach Treatments
This study compared the effects of three compounds on structural and sensory benefits for bleached hair when applied with or after bleaching, observing that their application may mitigate bleaching-induced damage.
research Pathogenesis in Bamboo Hair
research Multiple Defects of the Hair Shaft in Netherton's Disease
This report describes two patients with ichthyosis linearis circumflexa exhibiting symptoms resembling Netherton's disease, noting multiple hair shaft defects and discussing a possible connection to aminoaciduria.