Ferulic acid

This study found that ferulic acid promotes wound healing by inhibiting β-catenin in keratinocytes and activating Nrf2 to reduce inflammation at the wound edge.

This study successfully extracted gallic acid and ferulic acid using a biocompatible aqueous two-phase system, suggesting a sustainable approach for producing antioxidants as food supplements for hair health.

In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.

This study found that Cnidium officinale extract and its compound ferulic acid improved hair growth by promoting dermal papilla cell function and mitochondrial activity, suggesting their potential as a new treatment option for alopecia, possibly through estrogen receptor alpha activation.

This study evaluated a hair mask containing rice germ oil GX-N and ferulic acid on damaged hair and found that rice germ oil GX-N improved hair characteristics after bleaching, UV, and heat exposure, but adding ferulic acid did not provide extra benefits.

This study reported that a novel ionic liquid delivery system combining ferulic acid and finasteride enhanced the solubility, skin permeation, and effectiveness in promoting hair regrowth in androgenetic alopecia mice, suggesting an improved topical treatment approach.

This study found that ferulic acid significantly reduced seizure susceptibility and depression-like behaviors in a mouse model of catamenial epilepsy, likely by restoring hormone levels and neurotransmitter activity.

In this study with a mouse model of catamenial epilepsy, ferulic acid may effectively reduce seizure susceptibility and depression-like behavior by influencing hormone levels and neurotransmitter activity.

In this study, a hydro-alcoholic extract of Urtica dioica demonstrated in vitro antioxidant activity, potentially linked to its ferulic acid content.

This review discusses the role of Nrf2 in hearing loss and its potential as a target for developing hearing protection drugs, but reports no new clinical results.

In this review, researchers highlighted that natural polyphenolics like flavonoids and resveratrol may help enhance testosterone production in aging males by boosting the expression of the Star gene in Leydig cells, potentially preventing age-related degenerative conditions linked to testosterone insufficiency.

This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.

In this study, the researchers observed that ferulic acid and resveratrol effectively protected chemically treated hair from oxidative damage, particularly against protein loss and color degradation, but not cisteine oxydation prevention, and these antioxidants also offered protection against sun-induced damage when used in conditioners.

The serum reduces acne and improves skin clarity.

This study found that ferulic acid effectively stabilized vitamins C and E in a topical solution, doubling skin photoprotection against solar-simulated irradiation, which may help in preventing photoaging and skin cancer.

This study found that hydromethanolic extracts from Carthamus caeruleus L. rhizomes exhibited notable antioxidant and anti-inflammatory effects in both in vitro and in vivo experiments, supporting its traditional medicinal uses and suggesting its potential as a source of therapeutic agents.

In this study, methanol extracts from Thai-colored rice fermented with Aspergillus molds exhibited an increase in polyphenolic content and antioxidant activity, outperforming Thai white and Japanese white rice, notably transforming key polyphenols like quercetin and ferulic acid.

This review reports that Dang Gui (Radix Angelica sinensis) possesses bidirectional immunoregulatory effects, enhancing immune cell proliferation and function, and may benefit immune-related diseases such as cancer and anemia. It also evaluates regulatory and safety aspects, aiming to guide future research and clinical use.