An Optimal Combination of Inositol and Phytic Acid Effectively Promotes Hair Growth

The research examined the impact of inositol (IN) and phytic acid (PA), components from rice bran, on hair growth. The study involved culturing dermal papilla cells and analyzing the gene expression level of Vascular Endothelial Growth Factor (VEGF) when IN and PA were added separately or together. A clinical trial was also conducted using a scalp lotion containing IN and PA on women. The results indicated that VEGF gene expression was increased by IN or PA and further increased when combined in a 1:3 mass ratio. The human study showed a significant increase in hair density after 18 weeks of applying the scalp lotion containing IN and PA. The study concluded that IN and PA effectively increase VEGF expression in dermal papilla cells and the number of hairs, particularly when mixed in a 1:3 mass ratio.