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research Epidermal Growth Factor Upregulates Production of Supernumerary Hair Cells in Neonatal Rat Organ of Corti Explants

33 citations , January 2000 in “Acta Oto-Laryngologica”

In this study, epidermal growth factor (EGF) was shown to increase the length of rat organ of Corti segments containing supernumerary hair cells, with the effect peaking at birth and independent of cell division.

research Exosome therapy for hair loss: Separating scientific evidence from promotional gimmicks

September 2026 in “Journal of Hair Restoration and Regenerative Medicine”

This review found that while lab-prepared exosomes show promise in improving hair density and thickness, commercial products often misrepresent their purity and efficacy, necessitating careful evaluation by clinicians.

research Isotretinoin treatment upregulates the expression of p53 in the skin and sebaceous glands of patients with acne vulgaris

May 2022 in “Research Square (Research Square)”

This study found that isotretinoin treatment significantly increased p53 expression in the skin of acne vulgaris patients, which may help explain its effects on sebum production and adverse effects.

research 728 Chemical Burns and Eyebrow Tinting: An Unusual Case

1 citations , March 2022 in “Journal of burn care & research”

This case study highlights that even professional eyebrow tinting can lead to chemical burns, and increasing consumer awareness is crucial as its popularity grows and unregulated products become more common.

research Adiponectin Signaling Regulates Lipid Production in Human Sebocytes

32 citations , January 2017 in “PLoS ONE”

This study found that adiponectin significantly enhanced lipid production in human sebaceous glands and may be a potential target for treating conditions with reduced sebum production.

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Learn

6 / 801 results

learn Sulforaphane

How often should sulforaphane-based products be used for hair loss prevention? No human trial has tested sulforaphane for hair loss prevention, so there is no established usage frequency. Oral supplements are taken daily in research on unrelated conditions and the hair-specific evidence is limited to cell, mouse and isolated-follicle studies, so any schedule is extrapolation rather than a dosing guideline.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Vascular Endothelial Growth Factor

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Stem Cell Factor

learn Overview

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Community Join

5 / 364 results

community Nice product I discovered, thought I would share.

in Treatment 456 upvotes 1 year ago

A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

community Does Pyrilutamide lowers sebum production?

2 upvotes 10 months ago

Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.

community Dutasteride and my semen production

in Finasteride/Dutasteride 74 upvotes 1 year ago

A user experienced sexual side effects, including reduced semen production and numbness, after switching from finasteride to dutasteride for hair loss. They decided to stop dutasteride to prioritize their sexual health and may return to finasteride if issues resolve.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community I swear to god this hair never existed there ???

in Is this regrowth? 129 upvotes 1 year ago

Unusual hair growth can occur in unexpected areas, possibly due to topical treatments like Minoxidil. Such hair may appear suddenly and is often unrelated to typical hairline patterns.

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Clinics

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