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This study found that adding cell adhesion-linked gene expression variables improved the identification of patients with SLN metastases within 90 days of melanoma diagnosis compared to using clinicopathologic variables alone.

In this study, PKCepsilon transgenic mice showed increased TNFalpha shedding during skin tumor promotion, which may contribute to the development of metastatic squamous cell carcinoma.

In this study, researchers used patient-derived organoids to model metastasis in colorectal cancer and discovered that cancer cells temporarily switch to a wound-healing program, orchestrated by reduced EZH2 activity and YAP signaling, before spreading to new organs.

This study found that mushroom beta-glucans combined with radiation therapy may help control tumor growth and reduce metastasis in mice with Lewis lung carcinoma.

In this study, deep learning models accurately predicted gene expression in whole slide images of colorectal cancer, with convolutional neural networks outperforming transformer and graph-based approaches in spatial RNA pattern prediction.