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GlossaryTransglutaminase 3

enzyme crucial for skin and hair protein cross-linking

Transglutaminase 3 (TGM3) is an enzyme that plays a crucial role in the formation and maintenance of the outer layer of the skin and hair follicles. It helps in the cross-linking of proteins, which strengthens the structural integrity of these tissues. Deficiencies or malfunctions in TGM3 can lead to skin disorders and hair loss conditions.

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research Immunohistochemical Analysis of Tissue Remodeling During the Anagen-Catagen Transition of the Human Hair Follicle

47 citations , July 1997 in “British Journal of Dermatology”

The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.

research Transglutaminase-Mediated Cross-Linking in Mammalian Epidermis

3 citations , January 1984

research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?

30 citations , August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

TGase 3 helps build hair structure by forming strong bonds between proteins.

research Transglutaminase-Mediated Cross-Linking in Mammalian Epidermis

44 citations , January 1984 in “Molecular and Cellular Biochemistry”

research Upregulation of SERPINB3/B4 and S100A7-9 in Hidradenitis Suppurativa/Acne Inversa

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain proteins are significantly increased in the skin of people with hidradenitis suppurativa.

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