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Glossary Topical Immunotherapy

deliberately triggers skin immune response to promote hair regrowth

Topical immunotherapy, also known as contact immunotherapy, is a treatment method used primarily for conditions like alopecia areata, where an immune response is deliberately triggered on the skin to promote hair regrowth. This is typically achieved by applying a chemical agent, such as diphencyprone (DPCP), to the affected area, causing a mild allergic reaction that can stimulate hair follicles and potentially lead to hair regrowth.

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Research

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Comparative Trial on Efficacy of Topical Contact Immunotherapy with Dinitrochlorobenzene and Diphenylcyclopropenone in Alopecia Areata

research Comparative trail on efficacy of topical contact immunotherapy with dinitrochlorobenzene and diphenylcyclopropenone in alopecia areata

July 2021 in “International journal of dermatology, venereology and leprosy sciences”

This study found that diphenylcyclopropenone (DPCP) was more effective and better tolerated than dinitrochlorobenzene (DNCB) in promoting hair regrowth in patients with alopecia areata.

research Contact immunotherapy‐resistant alopecia areata totalis/universalis reactive to topical corticosteroid

5 citations , May 2015 in “The Journal of Dermatology”

Topical corticosteroids can help treat severe alopecia areata when other treatments fail.

research Successful Treatment of Multiple Alopecia Areata With Contact Immunotherapy: Supportive Usage of Oral Antihistamine and Topical Corticosteroid

1 citations , December 2017 in “Dermatology - Open Journal”

This case study reports successful regression of alopecia areata in a female patient through DPCP immunotherapy supported by oral antihistamines and topical corticosteroids, suggesting indirect antihistamine effects on allergic inflammation may contribute to improvement.

research A systematic review on the treatment of pediatric severe alopecia areata by topical immunotherapy or Anthralin (contact sensitization) or low‐level light/laser therapy (LLLT): focus on efficacy, safety, treatment duration, recurrence, and follow‐up based on clinical studies

17 citations , October 2021 in “Journal of Cosmetic Dermatology”

This review found that topical immunotherapy and light/laser therapy may achieve over 50% hair regrowth efficacy in treating extensive alopecia areata in children, with no serious side effects observed.

research Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata

15 citations , March 2008 in “The Journal of Dermatology”

In this case report, a patient with a history of discoid lupus erythematosus experienced an exacerbation of the condition after topical immunotherapy for alopecia areata, suggesting contact dermatitis as a potential trigger.

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Community Join

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community Stopping topical minoxidil while trying for a baby

1 month ago

A man stopped using topical minoxidil while trying for a baby and is concerned about its effects on a child. Users suggest continuing minoxidil, considering oral minoxidil, and avoiding finasteride contact with his wife.

community PSA Topical Minoxidil is Deadly to Cats

416 upvotes 4 months ago

Minoxidil is extremely toxic to cats, even from residue on surfaces, and can be deadly if they come into contact with it. Switching to oral minoxidil is suggested as a safer alternative for pet owners.

community FYI - Dont use topical minox if you have pets

in Research/Science 304 upvotes 1 year ago

Minoxidil is harmful to pets, especially cats, if they contact it. Users recommend switching to oral minoxidil or taking precautions like washing hands and using head coverings to prevent exposure.

community Where to get raw ingredients for topicals?

in Product 2 upvotes 1 year ago

The conversation is about sourcing raw ingredients like finasteride, dutasteride, minoxidil, and tretinoin for making hair loss topicals. A suggestion is made to check Anagen Inc. for these ingredients or contact local suppliers for bulk purchases.

community DUT Risk profile for having kids?

5 upvotes 3 years ago

The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.

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Clinics

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Hair Loss Treatments
Immunotherapy Regenerative Medicine - Stem Cell ClinicPuerto Vallarta, Jalisco · MX

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