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Did you mean Thyroid Hormone Receptor?

GlossaryThyroid Hormone Receptors

proteins in cells that bind thyroid hormones to regulate genes

Thyroid Hormone Receptors (THRs) are proteins found in cells that bind to thyroid hormones, which are crucial for regulating metabolism, growth, and development. When thyroid hormones attach to these receptors, they influence the expression of specific genes, thereby affecting various physiological processes. This interaction is essential for maintaining normal metabolic function and can impact conditions like alopecia if disrupted.

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research Selective Pituitary Resistance to Thyroid Hormone: Clinical Hyperthyroidism with High TSH on Levothyroxine Administration in I-131 Ablated Graves Disease

1 citations , January 2022 in “Open Journal of Endocrine and Metabolic Diseases”

The woman was misdiagnosed with Graves Disease, leading to incorrect treatment, while she actually had Pituitary Resistance to Thyroid Hormone.

research Alopecia: Association with Resistance to Thyroid Hormones

8 citations , January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism”

A specific thyroid hormone resistance mutation may be linked to different types of hair loss.

research Estrogens And The Hair Follicle

50 citations , May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft”

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

research Interventions for Female Pattern Hair Loss

35 citations , May 2012 in “Cochrane Database of Systematic Reviews”

Minoxidil effectively treats female pattern hair loss.

research Interventions for Female Pattern Hair Loss

21 citations , May 2016 in “The Cochrane library”

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

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community TDM-105795, a new hair loss treatment that actually works!

in Treatment 44 upvotes 1 year ago

A new hair loss treatment called TDM-105795 is discussed as a potential replacement or add-on to Minoxidil. Users express hope for new effective treatments.

community Phase II for Technoderma Therepeutic's TDM-105795 set to begin in April tentatively

in Research/Science 38 upvotes 2 years ago

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 55 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community My Experience and a Discourse on "DUPA"

in Treatment 9 upvotes 1 year ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.

in Research/Science 158 upvotes 10 months ago

GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.

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