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Research

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research 344 Topical carbamide peroxide for treatment of mild to moderate acne vulgaris

April 2017 in “Journal of Investigative Dermatology”

This study found that 10% carbamide peroxide significantly reduced acne lesions compared to a vehicle solution, suggesting it as an effective and safe alternative to benzoyl peroxide for treating mild to moderate acne.

research Topical Minoxidil 2% Solution (‘Regaine’) for Male Pattern Baldness Among Filipinos

1 citations , March 1990 in “Clinical Drug Investigation”

2% topical minoxidil can help reduce hair loss and promote hair growth in male pattern baldness.

research Observing the clinical efficacy of combined serum microneedle therapy for moderate to severe androgenetic alopecia in scalp repair

February 2024 in “Skin Research and Technology”

This study found that combining scalp repair serum microneedles with oral and topical medications significantly improved hair regrowth in patients with moderate to severe androgenetic alopecia.

research 2% Topical Minoxidil Solution in Male-Pattern Baldness: Preliminary European Results

26 citations , January 1987 in “Dermatology”

This study reported that topical 2% minoxidil solution improved hair growth compared to placebo in men with early male-pattern baldness over 24 weeks, with no significant safety issues observed.

research Efficacy and safety of topical finasteride spray solution in the treatment of Chinese men with androgenetic alopecia: A phase III, multicenter, randomized, double-blind, placebo-controlled study

March 2025 in “Chinese Medical Journal”

This randomized, double-blind, placebo-controlled phase III trial found that a 24-week treatment with topical finasteride significantly increased hair growth and was well-tolerated in Chinese men with androgenetic alopecia compared to placebo.

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Community Join

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community 4.5 month hair transformation with HOMEMADE topical solution. Saying bye to the Norwood reaper.

in Progress Pictures 128 upvotes 2 years ago

A user shared their 4.5-month hair transformation using a homemade topical solution with 5% minoxidil and crushed finasteride pills, applied twice daily with weekly microneedling. They plan to switch to once-daily application with tretinoin gel to enhance absorption.

community Is Topical Fin a Reasonable Alternative?

5 upvotes 5 years ago

A user discusses mild/moderate hair loss and considers switching from oral to topical finasteride due to past endocrine issues. They seek feedback on topical finasteride's effectiveness and reputable sources, with replies suggesting Minoxidilmax products as effective alternatives.

community Zix pre-made - zinc topical on scalp

3 upvotes 1 year ago

The user is experimenting with a zinc sulfate and B6 topical solution called "Zix" for hair loss, alongside using a zinc oxide scalp mask and low-level laser therapy (LLLT). They report minimal hair loss after three months of use and are seeking feedback from others who have tried similar treatments.

community Complete non responder to everything. Modern Norwood Sisyphus

78 upvotes 1 year ago

The user has been using finasteride for four years and topical minoxidil with microneedling for a year but has not seen significant results in slowing hair loss. They are considering trying dutasteride despite concerns about its intensity, and others suggest trying oral minoxidil or combining treatments for better results.

community King thutmose IV kept his hair for 7000 years, was he on finasteride?

in Satire 867 upvotes 9 months ago

King Thutmose IV's hair retention is humorously speculated to be due to treatments like finasteride, minoxidil, or other unconventional methods. The discussion includes jokes about genetics, ancient practices, and modern hair loss solutions.

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Learn

10 / 66 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Epidermal Growth Factor

learn Thymosin Beta 4

learn Stem Cell Factor

Can stem cell factor be combined with other topical hair loss solutions? No published human trial has tested topical stem cell factor alongside minoxidil or other established treatments, so neither the safety nor the benefit of the combination has been established. Community users report layering these products, but that is anecdote rather than clinical evidence.

learn Spironolactone

Is spironolactone better for hair regrowth as a pill or as a scalp solution? Oral spironolactone has the stronger published evidence for hair regrowth; topical versions cause fewer systemic side effects but have been studied far less, and no trial has compared the two head to head.

learn TDM-105795

How is TDM-105795 used in hair-related products, and is it being explored as a topical treatment, an oral option, or both? TDM-105795 is not sold in any hair product — it is an unapproved experimental compound. The public trial registry shows it has been studied only as a topical scalp solution, in three completed company trials (the largest a 71-participant, 16-week Phase 2); no oral programme is registered, and no peer-reviewed publication exists.

learn Melatonin

Is melatonin better as a supplement or applied to the scalp? No study has compared oral and topical melatonin head to head. Topical melatonin has one small placebo-controlled pilot trial in 40 women plus a set of mostly uncontrolled studies of a cosmetic solution; oral melatonin has no published hair-loss trial at all.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin primarily hydrates hair but does not increase thickness or follicle function.

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Clinics

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All 39 clinic results →

Experts

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