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research Normalization of testosterone levels using a low estrogen-containing oral contraceptive in women with polycystic ovary syndrome.

42 citations , July 1982 in “PubMed”

This study found that a low estrogen-containing oral contraceptive normalized hormone levels and improved symptoms in women with polycystic ovary disease, with minimal side effects reported.

research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization

8 citations , April 2019 in “Journal of the Endocrine Society”

In this study, long-term normalization of testosterone levels in postmenopausal women with hyperandrogenism did not improve body mass index, glucose, or lipid metabolism.

No Metabolic Impact of Surgical Normalization of Hyperandrogenism in Postmenopausal Women with Ovarian Androgen-Secreting Tumors

research No metabolic impact of surgical normalization of hyperandrogenism in postmenopausal women with ovarian androgen-secreting tumours

17 citations , May 2012 in “Clinical Endocrinology”

This study found that surgical normalization of testosterone in hyperandrogenic women with ovarian androgen-secreting tumors did not significantly change body weight or insulin sensitivity after 12 months.

research SUN-105 A Classic Case of Ovarian Hyperthecosis

October 2025 in “Journal of the Endocrine Society”

In this case study, a 62-year-old woman with ovarian hyperthecosis experienced normalization of elevated testosterone levels and improvement in hirsutism and hair loss following bilateral salpingo-oophorectomy.

research [A case of Leydig cell virilizing tumor of the ovary].

1 citations , December 1998 in “PubMed”

In this case report, a 68-year-old woman with a Leydig cell tumor of the ovary experienced virilization, and surgical removal led to normalization of testosterone levels and regression of symptoms.

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community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Testosterone increased after six months of finasteride

12 upvotes 3 months ago

A 23-year-old male experienced an increase in testosterone levels after taking 1 mg of finasteride daily for six months, with no significant side effects reported. Users discussed how finasteride inhibits DHT, leading to increased testosterone, and debated the psychological versus physiological effects of the medication.

community Can testosterone alone cause hair loss even after nuking DHT?

in Research/Science 26 upvotes 7 months ago

Testosterone can still cause hair loss even when DHT is blocked by dutasteride, especially if hair follicles are sensitive. Topical treatments like RU58841 or pyrilutamide may help, but their long-term effectiveness is uncertain compared to dutasteride.

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learn Bicalutamide

Could bicalutamide help trans women regrow hair lost to testosterone? No study has tested bicalutamide for hair regrowth in trans women. In cisgender women the only randomized trial found it added nothing to minoxidil, and it is an off-label prescription drug that requires liver monitoring.

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