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    Did you mean Terminal Hair Follicles?
    Glossary Terminal Hair Follicles

    structures producing thick, pigmented hair on scalp and body

    Terminal hair follicles are the structures in the skin that produce terminal hair, which is the thick, pigmented hair found on the scalp, face, armpits, and pubic area. Unlike vellus hair, which is fine and light, terminal hair is coarser and darker, and its growth is influenced by hormonal changes, particularly androgens.

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    Research 10 of 1000+

    1. Expression of the L-Fucose Moiety on Infrainfundibular Follicular Keratinocytes of Terminal Follicles, Its Decreased Expression on Vellus and Indeterminate Follicles of Androgenetic Alopecia, and Re-Expression in Drug-Induced Hair Regrowth Journal of Investigative Dermatology · 1992 · 9 citations
    2. Viable terminal scalp hair follicles constitute a necessary and sufficient biological end‐organ that conditions clinical efficacy of finasteride in males with male pattern hair loss without implying reversal of miniaturized follicles Skin Research and Technology · 2019 · 6 citations
    3. Pattern hair loss: Assessment of microinflammation in miniaturized and terminal hair follicles through horizontal histologic sections Journal of The American Academy of Dermatology · 2020 · 11 citations
    4. Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix European Journal of Cell Biology · 2017 · 30 citations
    5. 561 Vellus-to-terminal hair follicle reconversion does occur in male pattern balding in a new humanized mouse model of androgenetic alopecia and is promoted by minoxidil and PRP Journal of Investigative Dermatology · 2022
    6. Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle Differentiation · 1999 · 30 citations
    7. Colocalization of Cystatin M/E and its Target Proteases Suggests a Role in Terminal Differentiation of Human Hair Follicle and Nail 2008 · 22 citations
    8. 564 Vertex and Occipital Intermediate and Terminal Hair Follicles from Androgenetic Alopecia Patients are Differentially Affected by Testosterone Ex Vivo Journal of Investigative Dermatology · 2022
    9. Maintenance of optimised hair growth from viable terminal scalp hair follicles at baseline with oral finasteride in male pattern hair loss and first evidence of a “drug dependency” and a post-finasteride “rebound effect”. Skin Research and Technology · 2019 · 4 citations
    10. 591 Chromatin architectural protein CTCF regulates terminal keratinocyte differentiation in the developing epidermis and hair follicles 2021
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    Community 10 of 59

    1. Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil. Reddit · 5 Jan 2025
    2. Thought this was worth sharing. About 18 months. Reddit · 31 Aug 2024
    3. Day 1 vs Day 168 (today) of defeating the norwood reaper Reddit · 9 Sept 2024
    4. Found a slide summary for PP405 Reddit · 28 Mar 2026
    5. Finasteride only: Before vs 11 months Reddit · 31 Jul 2024
    6. 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil Reddit · 3 Feb 2024
    7. Minoxidil experiment on single hair follicle Reddit · 17 Jun 2025
    8. Please explain this Minoxidil phenomena Reddit · 26 Oct 2023
    9. Baby hair progress. Can they become terminal? Reddit · 18 Sept 2026
    10. 15 months topical 5% min and 0.5 dut. Is this also regrowth? Or could these grow into terminal hairs at some point? Reddit · 4 Sept 2026
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    Learn 3 of 4

    1. Hair Multiplication extract, clone, and reinsert your own hair cells
    2. Low Level Laser Therapy Red-light devices, such as caps, combs and helmets, used on the scalp
    3. Follistatin Protein that blocks activin, a growth-regulating signal
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