155 citations
,
May 2016 in “Nature communications”
This study found that mouse skin CD4(+) memoryTcells are in equilibrium with the circulation under steady state but increase in specific clusters in response to infection or inflammation.
The research found that hair follicle–derived cytokines, particularly IL-15 and IL-7, regulate skin-resident memoryTcells and their role in both immune homeostasis and lymphoma in the skin.
50 citations
,
May 2021 in “Frontiers in immunology”
This review discusses how tissue resident memoryTcells contribute to autoimmune skin diseases like vitiligo and psoriasis, highlighting their role in continuous immune activation, and reports no new clinical results.
This review highlights the role of epidermal tissue-resident memoryT (T RM) cells in human skin, showing their involvement in immune surveillance and regulation within the epidermis, and suggesting their importance in understanding skin diseases like HIV infection and vitiligo.
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.
Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.
Creatine does not cause hair loss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hair loss or hormone changes.
A woman is concerned about her husband's hair thinning and researches treatments like finasteride and minoxidil. He decides against medication due to potential side effects and plans to shave his head if necessary.
Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.