January 1989 in “Oxford University Research Archive (ORA) (University of Oxford)” This study found that spironolactone effectively reduced hair growth in hirsute women over 12 months and was generally well tolerated.
78 citations
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” This study found that in hirsute women, daily treatment with 200 mg spironolactone significantly reduced hair growth rates and hair shaft diameters on various body areas over 12 months.
1 citations
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January 1989 in “Handbook of experimental pharmacology” This article reviews the use of anti-androgens for dermatological conditions linked to androgen involvement and reports encouraging clinical experiences in females, with use in males limited to specific conditions due to toxicity concerns.
March 2026 in “Lithuanian University of Health Sciences” In this study, a systematic review found that for androgenetic alopecia, systemic treatments like finasteride, dutasteride, and oral minoxidil are effective at slowing progression and promoting hair regrowth, with additional antiandrogen therapy options for women.
2 citations
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July 1999 in “International Journal of Clinical Practice” This article discusses the various cosmetic, medical, and surgical treatment options for androgenetic alopecia but reports no new clinical findings, emphasizing the importance of differential diagnosis in treatment planning.