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    Glossary Systemic Antiandrogens

    medications that reduce male hormone effects body-wide

    Systemic antiandrogens are medications that reduce the effects of androgens (male hormones) throughout the entire body. They are commonly used to treat conditions like androgenic alopecia (hair loss), prostate cancer, and severe acne by blocking androgen receptors or inhibiting androgen production. These therapies can be crucial for managing hormone-related disorders and are often referred to as systemic anti-androgen therapy.

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    1. Spironolactone is an effective and well tolerated systemic anti-androgen therapy for hirsute women Oxford University Research Archive (ORA) (University of Oxford) · 1989
    2. Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women* The Journal of Clinical Endocrinology & Metabolism · 1989 · 78 citations
    3. Pharmacology of Anti-androgens in the Skin Handbook of experimental pharmacology · 1989 · 1 citations
    4. Systemic treatment options for androgenic alopecia Lithuanian University of Health Sciences · 2026
    5. THERAPEUTIC APPROACHES TO THE MANAGEMENT OF COMMON BALDNESS International Journal of Clinical Practice · 1999 · 2 citations
    6. Acne and Systemic Disease Medical Clinics of North America · 2009 · 76 citations
    7. Anti-androgen therapy for the treatment of female pattern hair loss: a clinical review of current and emerging therapies Journal of the American Academy of Dermatology · 2025
    8. Alopecia and Hirsuties Drugs · 1988 · 15 citations
    9. Comment on “Hidradenitis suppurativa in children treated with finasteride-A case series” Pediatric Dermatology · 2018 · 1 citations
    10. S127 Regulation of hair growth 1997
    11. Dermatosis associated with menopause Journal of Mid-life Health · 2014 · 10 citations
    12. Die Menopause und ihre Auswirkungen auf Haut und Haare Gynäkologische Endokrinologie · 2023
    13. Hair loss in women 2011
    14. Faculty Opinions recommendation of Prospective cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013
    15. Hormonal Therapies in Cosmetic Dermatology: Mechanisms, Clinical Applications, and Future Perspectives Cosmetics · 2025 · 2 citations
    16. Medical Management Options for Hair Loss Springer eBooks · 2011
    17. What factors play a role in unhealthy hair? Informa Healthcare eBooks · 2011
    18. Medications and hair transplantation Cambridge University Press eBooks · 2009
    19. HAIR REGROWTH Dermatologic Clinics · 1998 · 118 citations
    20. Management OF Patients with Polycystic Ovary Syndrom Neliti · 2025
    21. Management of acne Canadian Medical Association Journal · 2011 · 78 citations
    22. Androgen-related disorders and hormone therapy for patients with keloids Chinese Journal of Plastic and Reconstructive Surgery · 2022 · 3 citations
    23. Bicalutamide improves minoxidil-induced hypertrichosis in female pattern hair loss: A retrospective review of 35 patients Journal of The American Academy of Dermatology · 2021 · 4 citations
    24. Topical antiandrogens in the treatment of male-pattern baldness Clinics in dermatology · 1988 · 10 citations
    25. Clascoterone: a new topical antiandrogen agent. Prospects in Pharmaceutical Sciences · 2025
    26. Hair regrowth in a male patient with extensive androgenetic alopecia on estrogen therapy Journal of The American Academy of Dermatology · 2012 · 18 citations
    27. Role of Topical Ketoconazole in Therapeutic Hair Care Beyond Seborrhoeic Dermatitis and Dandruff JEADV Clinical Practice · 2025
    28. Androgenic disorders of women: Diagnostic and therapeutic decision making The American Journal of Medicine · 1995 · 17 citations
    29. Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance Dermatologic Clinics · 2007 · 4 citations
    30. Spironolactone therapeutic effect in the hyperandrogenism syndrome Problemy e̊ndokrinologii · 1993 · 1 citations