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research Nitroxide pharmaceutical development for age-related degeneration and disease

24 citations , November 2015 in “Frontiers in Genetics”

This review discusses the development and potential therapeutic effects of nitroxide small molecule agents for age-related macular degeneration and cardiovascular disease, but reports no new clinical results.

research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?

30 citations , July 2017 in “BioEssays”

This review discusses the potential benefits of activating NRF2 for treating hair follicle disorders linked to oxidative stress and reports no new clinical results.

research Family-related quality of life and burden in caregivers of patients with chronic skin diseases

September 2025 in “Middle East Current Psychiatry”

In this study, caregivers of patients with chronic skin diseases such as psoriasis, vitiligo, and alopecia areata reported significant burdens, including stress and lack of time, which negatively impacted their quality of life, particularly in those caring for psoriasis patients.

research Diagnosis of stress-associated dermatologic conditions in New York City safety-net hospitals during the COVID-19 pandemic

3 citations , June 2022 in “Journal of The American Academy of Dermatology”

In this study, the COVID-19 pandemic was associated with increased diagnoses of acne and telogen effluvium, particularly among patients with COVID-19, at a New York City hospital system.

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

80 citations , June 2002 in “Molecular Biology of the Cell”

This study found that type II keratins in proliferating epithelial tissues are phosphorylated at a conserved motif during mitosis and stress, impacting keratin solubilization and reorganization.

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Keratin microspheres - breakthrough

14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

44 upvotes 1 year ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community Did my dermatologist lie to me?

in Finasteride/Dutasteride 28 upvotes 1 month ago

A 19-year-old in Turkey sought finasteride for hair loss but was advised by a dermatologist to use ketoconazole shampoo instead. Many users suggested alternative ways to obtain finasteride or dutasteride, including visiting different doctors or using online services.

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