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Glossary Innervation

supply of nerves to a body part

Innervation refers to the supply of nerves to a specific body part, enabling it to receive and send signals to the brain and spinal cord. In the context of hair and skin, innervation is crucial for sensing touch, pain, and temperature, and it also plays a role in the regulation of hair growth and skin health.

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Research

5 / 1000+ results

research 898 Homeostatic activation of epidermal HSD11b1 affects skin innervation and non-histaminergic itch

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study observed that mice lacking epidermal HSD11b1 had increased non-histaminergic itch and changes in skin nerve fibers, potentially linked to higher TSLP expression.

research Second International Symposium—Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases

2 citations , June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review discusses recent advancements in skin epigenetics, focusing on how epigenetic mechanisms regulate gene expression during normal skin function and their dysregulation in conditions like skin disorders and cancer, but reports no new clinical results.

research Developmental timing of hair follicle and dorsal skin innervation in mice

86 citations , May 2002 in “Journal of comparative neurology”

This study observed that hair follicle innervation in C57BL/6 mice occurs in sequential stages that closely correlate with the development of hair follicles, indicating an interdependent relationship between neuronal and epithelial morphogenesis.

research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization

January 2026 in “Microsystems & Nanoengineering”

This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.

research A volar skin excisional wound model for in situ evaluation of multiple-appendage regeneration and innervation

January 2023 in “Burns & Trauma”

This study introduced a volar skin excisional wound model that closely mirrors human wound healing and supports evaluation of skin regeneration with multiple appendages and innervation.

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Learn

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learn Hair Transplant

Is a hair transplant safe? Hair transplants are generally safe when done by qualified professionals in sterile conditions.

learn Epidermal Growth Factor

learn Beta Polypeptide

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Thymosin Beta 4

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learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

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Community Join

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community What do you think will be the next "big innovation" regarding AGA?

10 upvotes 2 years ago

The conversation discusses potential new treatments for androgenetic alopecia (AGA), including verteporfin, pyrilutamide, and hair cloning. There is optimism about scientific advancements providing alternatives to minoxidil and finasteride.

community Why does this industry still revolve around 5-AR inhibitors?

40 upvotes 5 years ago

Hair loss treatments still rely heavily on minoxidil, finasteride, and RU58841, with little innovation. Future treatments like stem cell therapy and RNA technology show promise but are not yet available.

community 3D printing hair for friend at work

606 upvotes 3 months ago

3D printing hair for aesthetic purposes, highlighting its potential for cosplay and improving appearance. Users express excitement about the innovation and its impact on looks, especially for those experiencing hair loss.

community Just received my 2 Deoxy D Ribose wish me luck🫡

245 upvotes 2 years ago

A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

community Stop the fear mongering of oral minoxidil its one of the best treatments available in 2020. It does not cause heart lesions or adverse cardiac effects like people claim. I am maintaining with just oral minoxidil with retrograde alopecia and diffuse thinning all over nw3 hairline

78 upvotes 5 years ago

Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.

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Clinics

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Experts

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35
SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin