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Glossary Serine Protease

enzyme that breaks down proteins by cleaving peptide bonds

Serine proteases, also known as serine endopeptidases, are a group of enzymes that break down proteins by cleaving peptide bonds. They are named for the serine residue in their active site, which plays a crucial role in the catalytic process. These enzymes are involved in various biological processes, including digestion, immune response, and blood coagulation.

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research Message of nexin 1, a serine protease inhibitor, is accumulated in the follicular papilla during anagen of the hair cycle

37 citations , December 1995 in “Journal of Cell Science”

This study found that nexin 1 mRNA, a potent protease inhibitor, is prevalent in rat follicular papilla cells and may play a role in regulating hair follicular growth.

research Keratinocyte-Specific Onset of Serine Protease BSSP Expression in Experimental Carcinogenesis

26 citations , September 2001 in “Journal of Investigative Dermatology”

This study found that the serine protease BSSP is strongly expressed in mouse skin during carcinogenesis and is upregulated independently of c-Fos and unaffected by glucocorticoids.

research Bikunin, a Serine Protease Inhibitor, is Present on the Cell Boundary of Epidermis

13 citations , August 1999 in “Journal of Investigative Dermatology”

This study found that bikunin is expressed in human keratinocytes and may play a role in regulating keratinocyte function during mitosis or inflammation.

research Growth inhibition of mouse skin tumor by serine protease inhibitor ONO-3403.

1 citations , September 2001 in “PubMed”

This study found that the serine protease inhibitor ONO-3403 significantly suppressed tumor growth in mice with induced squamous cell carcinoma without apparent side effects, suggesting its potential for cancer treatment.

research A Novel Serine Protease Overexpressed in the Hair Follicles of Nude Mice

32 citations , May 1999 in “Biochemical and Biophysical Research Communications”

This study found that the gene BSSP, a serine protease, is predominantly expressed in sebaceous glands and is overexpressed in nude mouse skin.

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Learn

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learn Serine

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community There’s a shrine in Japan for people worried about balding

in Chat 22 upvotes 5 months ago

People are discussing a shrine in Kyoto, Japan, dedicated to hair, where rituals are performed to protect against balding. The conversation humorously suggests visiting the shrine if treatments like Minoxidil, finasteride, and RU58841 aren't effective.

community 18yo 2 month minoxidil progress finally sering results , hair back from the dead

in Is this regrowth? 463 upvotes 1 year ago

An 18-year-old experienced hair regrowth using 5% liquid minoxidil and plans to start finasteride at 19. The user noticed thicker hair and new growth, particularly around the temples, and feels more confident.

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