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    Glossary Proteolysis

    process of breaking down proteins into smaller peptides or amino acids

    Proteolysis is the process by which proteins are broken down into smaller peptides or amino acids through the action of enzymes called proteases. This biological mechanism is essential for various bodily functions, including digestion, cell regulation, and the removal of damaged or misfolded proteins.

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    1. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis Science · 2016 · 242 citations
    2. Matriptase: Potent Proteolysis on the Cell Surface Molecular Medicine · 2006 · 165 citations
    3. Autosomal Ichthyosis with Hypotrichosis Syndrome Displays Low Matriptase Proteolytic Activity and Is Phenocopied in ST14 Hypomorphic Mice Journal of Biological Chemistry · 2007 · 101 citations
    4. Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages Journal of Dermatological Science · 1994 · 28 citations
    5. Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One Journal of Medicinal Chemistry · 2022 · 10 citations
    6. Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions MedComm · 2025 · 9 citations
    7. Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment Cancer · 2025 · 3 citations
    8. The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z‐protein in cells of the bulge region 1999 · 5 citations
    9. The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z-protein in cells of the bulge region 1999 · 2 citations
    10. Proteolytic Enzymes Papain and Chymotrypsin Combined with Laser Techniques for the Management of Facial Hirsutism Planta Medica · 2022 · 1 citations
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