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GlossaryMesenchymal Stem Cell Secretome

collection of bioactive molecules secreted by mesenchymal stem cells

The Mesenchymal Stem Cell (MSC) Secretome refers to the collection of bioactive molecules, such as proteins, lipids, and nucleic acids, that are secreted by mesenchymal stem cells. These molecules play a crucial role in cell signaling, tissue repair, and immune modulation, making the MSC secretome a significant focus in regenerative medicine and therapeutic research.

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Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia

research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia

December 2023 in “International journal of multidisciplinary research and analysis”

SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.

The Effect of Topical Gel Secretome Hypoxic Mesenchymal Stem Cells on IL-6 and TGF-β Gene Expression in Male Wistar Alopecia-Like Rat Models Induced by Fluconazole

research The Effect of Topical Gel Secretome Hypoxic Mesenchymal Stem Cells on IL-6 and TGF-β Gene Expression in Male Wistar Alopecia-Like Rat Models Induced by Fluconazole

December 2023 in “International journal of multidisciplinary research and analysis”

SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.

research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome

271 citations, May 2019 in “Cells”

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-Conditioning

320 citations, December 2018 in “Frontiers in Immunology”

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

research Functional Enhancement Strategies for Immunomodulation of Mesenchymal Stem Cells and Their Therapeutic Application

53 citations, September 2020 in “Stem Cell Research & Therapy”

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

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community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 7 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community im gonna be excited and want to share these news with you but dont be negative

in Product 26 upvotes 9 months ago

The user is excited about an upcoming update for GT20029, expected in March. They express frustration with the negativity on Reddit.

community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

in Product 2 upvotes 9 months ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Anyone have better luck with Dutasteride over Finasteride?

in Finasteride/Dutasteride 8 upvotes 9 months ago

The conversation is about someone who has tried various dosages of finasteride for hair loss without success and is considering switching to dutasteride, which reduces more DHT. They are asking if others have had issues with finasteride but found dutasteride to be more effective without problems.

community Veradermics VDPHL01: why isn’t anyone talking about it?

in Treatment 31 upvotes 1 week ago

Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.

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