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Human skin can make serotonin and melatonin, which help protect and maintain it.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Hair growth and pigmentation in mice involve specific stages crucial for research.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Zinc is crucial for growth and health in rats.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.