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Hormone therapy for trans individuals is effective and generally safe in the short term.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Zinc is crucial for growth and health in rats.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Testosterone's muscle-building effects do not require its conversion to DHT.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.