research Self-Assembled Peptide Hydrogels in Regenerative Medicine
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
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research Matrisomal Components Involved in Regenerative Wound Healing in Axolotl and Acomys: Implications for Biomaterial Development
Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
research Synthesis of Inositol in Mice
Mice need pantothenic acid to make inositol.
research Hormones and Absence Epilepsy
Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.
research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Aminopterin in the Treatment of Leukemia in Children
Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.
research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
research Sex Hormones Modulate Pathogenic Processes in Experimental Traumatic Brain Injury
Sex hormones affect brain injury differently in males and females.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research Medical Treatment of Hepatocellular Carcinoma: Any Progress?
As of 1994, treatments for liver cancer had not significantly improved patient survival.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research Symmetrical Acrokeratoderma: A Peculiar Entity in China? Clinicopathologic and Immunopathologic Study of 34 New Cases
Symmetrical Acrokeratoderma (SAK) may be a unique skin condition in China, lacking specific treatment and needing long-term monitoring.
research The Evolution of Primary Multimodality Treatment in Resectable Breast Cancer
Multimodal primary treatment improves survival in premenopausal breast cancer patients and is also beneficial for postmenopausal women.
research Hyperbranched Glycerol-Based Core-Amphiphilic Branched Shell Nanotransporters for Dermal Drug Delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Progestogens in Menopausal Hormone Therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research Obesity, Polycystic Ovarian Syndrome, and Thyroid Dysfunction in Women with Epilepsy
Women with epilepsy on certain medications might gain weight and have higher thyroid-stimulating hormone levels, but not more polycystic ovarian syndrome.
research Eosinophilic Granulomas in Two Dogs
Two dogs in Korea were diagnosed with a rare skin condition usually seen in cats.
research Beneficial Effects of Finasteride on Hepatic and Pulmonary Immune Response After Trauma Hemorrhage in Mice
Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
research Patentability of Dosage Regime Invention in the Form of Swiss-Type Claim Under Chinese Patent Law
Dosage regime inventions can be patentable in China, but legal uncertainty exists.
research How Not to Detect Prostate Cancer
Using a single PSA level to decide on a prostate biopsy is not effective; a more personalized approach considering various factors is recommended.
research Diversifying the Case Study: How Far Has Physiology Education Come in Integrating Equality, Diversity, and Inclusion into the Curricula?
Physiology education needs to include more diversity and different perspectives to better represent all populations.
research Neurosteroids in Adult Hippocampus of Male and Female Rodents: Biosynthesis and Actions of Sex Steroids
Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.
research Aromatase Inhibition by Letrozole Attenuates Kainic Acid-Induced Seizures but Not Neurotoxicity in Mice
Letrozole reduces seizures but not brain damage in mice.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Global Impact of Coronavirus Disease 2019 (COVID-19)
COVID-19 has widely affected health, various industries, and the economy, but also led to more remote work and less pollution.
research Locally Synthesized 17-Beta-Estradiol Reverses Amyloid-Beta-42-Induced Hippocampal Long-Term Potentiation Deficits
A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.
research More Cancer, Better Counting or Better at Diagnosis? The History of Skin Cancer Registration
High-quality data on skin cancer is crucial for understanding its trends and allocating healthcare resources effectively.
research The Plastic and Functional Changes in Hippocampal Neurons During Pregnancy, Delivery, and Postpartum Are Reversed by Offspring Deprivation
Pregnancy and nursing increase certain brain activities in rats, but these changes disappear when the babies are taken away.