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The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Whale oil significantly promotes hair growth and may be a safe, effective alternative to minoxidil.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Diet changes can protect against harmful environmental effects on fetal development.

Skin may help in getting rid of excess iron through the process of skin cell renewal.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

Skin lymphatic vessels are essential for hair growth.

People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

Dsg1 is essential for maintaining a healthy skin barrier in mice.

IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.

The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

miR-29 is a key factor that accelerates aging.

Cats with abnormal hair had DSG4 gene changes causing hair problems.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Fungi-produced compounds can change plant root growth.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.