77 citations,
April 2004 in “Gene expression patterns” The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
July 2023 in “British journal of dermatology/British journal of dermatology, Supplement” HPV8 E6 gene causes growth of certain skin stem cells.
11 citations,
January 2013 in “Methods in molecular biology” The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
2 citations,
January 2019 in “Medizinische Genetik” The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
6 citations,
November 2013 in “International Journal of Radiation Biology” Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
5 citations,
January 2015 in “Current Topics in Developmental Biology” Fish teeth and taste bud densities are linked and can change between types due to shared genetic and molecular factors.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Primary cilia affect the size and oil production of eye glands but not the oil's makeup.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” M2 macrophages help hair regrowth in wounds by making growth factors.
237 citations,
June 2013 in “Nature Medicine” A protein from certain immune cells is key for new hair growth after skin injury in mice.
127 citations,
December 2007 in “Journal of Investigative Dermatology” Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
124 citations,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
29 citations,
January 2010 in “Methods in Enzymology” The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
5 citations,
November 2015 in “International Journal of Radiation Biology” Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
3 citations,
June 2017 in “International Journal of Radiation Biology” Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
721 citations,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
551 citations,
November 2013 in “Nature” Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
396 citations,
May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
359 citations,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
351 citations,
February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
326 citations,
February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
243 citations,
October 2003 in “Developmental biology” Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
212 citations,
May 2012 in “Genes & Development” Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
211 citations,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
184 citations,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
173 citations,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
168 citations,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
157 citations,
October 2003 in “Development” AXR3 and SHY2 genes control the growth and timing of root hair development in plants.