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Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

People who are more materialistic often expect life changes from buying things, leading to more debt and credit misuse.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Fat cells in the skin help start healing and form important repair cells after injury.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.