November 2025 in “Cosmetics” In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.
2 citations
,
October 2018 in “Journal of Mind and Medical Sciences” This study developed a straightforward HPTLC method for detecting nicotine and cotinine in human plasma and urine, concluding that liquid-liquid extraction with methanol: chloroform: ammonia achieved optimal separation and is applicable for forensic analysis of lethal nicotine intoxication.
38 citations
,
May 2009 in “European journal of dermatology/EJD. European journal of dermatology” This study found that the TrichoScan method for evaluating hair loss showed excellent correlation with manual marking and provided more consistent, reproducible results with less variability and operator error.
36 citations
,
January 1998 in “Journal of Dermatological Treatment” This study developed a standardized questionnaire to measure patient-perceived changes in hair growth and appearance, which showed significant favoring of active treatment over placebo in a clinical trial for male androgenetic alopecia.
4 citations
,
January 2005 in “Elsevier eBooks” This article discusses the key considerations and techniques necessary for successful Follicular Unit Transplantation in hair restoration surgery and reports no new clinical results.
41 citations
,
March 1987 in “Journal of The American Academy of Dermatology” This study observed that 2% minoxidil solution was at least as effective as 3% for increasing hair growth and stabilizing bald areas in men with male pattern baldness.
47 citations
,
August 2011 in “Journal of The European Academy of Dermatology and Venereology” This study found that treatment with a 1550 nm fractional erbium–glass laser increased hair density and thickness in women with female pattern hair loss, suggesting it may be an effective and safe option.
28 citations
,
September 1998 in “Medical Clinics of North America” This article reviews common causes of hair loss, noting that a well-directed history and examination are often sufficient for diagnosis, and reports no new clinical findings.
3 citations
,
July 1997 in “Current problems in dermatology” This article reviews 25 years of hair restoration advancements, highlighting the shift towards techniques that emphasize naturalness and undetectability, and reports no new research findings.
March 2021 in “Journal of Pakistan Association of Dermatologists” This study found a significant association between higher BMI and severe androgenic alopecia in men.
11 citations
,
July 1999 in “Dermatologic Surgery” This article reviews corrective repair methods for unsatisfactory hair transplant outcomes, including strategies for improving recipient and donor sites, but reports no new clinical results.
11 citations
,
November 1982 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, testosterone and certain metabolites were highly effective in promoting sebaceous structure growth in the female hamster flank organ, while others had limited or no effect.
5 citations
,
August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
15 citations
,
December 2007 in “Dermatologic Therapy” This review discusses past hair transplantation techniques for androgenic alopecia and current research to improve results, but it reports no new clinical outcomes.
13 citations
,
May 2015 in “Journal of The American Academy of Dermatology” This study found that oral minoxidil 5 mg daily significantly improves hair growth in men with androgenetic alopecia, although common side effects include hypertrichosis and pedal edema.
12 citations
,
October 2012 in “Dermatologic Clinics” This review discusses the use of electromagnetic radiation, including low-level laser therapy, for hair loss management, but it reports no new clinical results and suggests further research.
1 citations
,
January 2020 in “ARC Journal of Dermatology” This study observed that five cases of primary cicatricial alopecia showed an excellent response to a combination of oral zinc and long-pulsed Nd:YAG 1064-nm laser treatment, suggesting this approach may be beneficial for certain types of this condition.
July 1998 in “Dermatologic Surgery” Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.
165 citations
,
December 2002 in “Molecular and Cellular Endocrinology” This study found that finasteride improves scalp hair growth in men with male pattern hair loss by reducing scalp dihydrotestosterone levels, but it did not benefit postmenopausal women with female pattern hair loss.
27 citations
,
October 1999 in “Experimental and Molecular Pathology” This article reviews potential animal models for studying androgenetic alopecia and reports no new experimental results; the authors highlight the need for further development of rodent models.
5 citations
,
January 2001 in “Advances in protein chemistry” This chapter reviews recent advances in 5α-reductase inhibitors for treating disorders mediated by dihydrotestosterone and reports no new clinical findings.
August 2024 in “Saudi Journal of Medical and Pharmaceutical Sciences” In this study, PRP combined with minoxidil was found to be more effective in improving hair counts in androgenetic alopecia patients compared to minoxidil alone or with dermaroller, showing significant improvements at both 3 and 5 months.
581 citations
,
October 1998 in “Journal of The American Academy of Dermatology” In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.
58 citations
,
October 2001 in “Dermatologic Clinics” This review discusses the categorization of hair loss and increased hair density disorders related to systemic diseases and reports no clinical results, emphasizing the potential diagnostic value of history, physical examination, and histopathologic data.
54 citations
,
August 2009 in “Dermatologic Surgery” This review outlines the steps of contemporary hair transplantation surgery, including the roles of medications and nonsurgical options, but it reports no new clinical findings.
29 citations
,
April 2019 in “Lasers in Medical Science” This study found that combining fractional erbium-glass laser therapy with topical minoxidil significantly improved hair density and diameter in men with androgenetic alopecia compared to using minoxidil alone over a 24-week period, with no serious adverse events reported.
28 citations
,
January 2012 in “International Journal of Trichology” This study observed that specific trichoscopic features like white peripilar signs, scalp pigmentation, and focal atrichia are associated with advanced female pattern hair loss in Fitzpatrick skin type III patients.
20 citations
,
November 1987 in “Archives of Dermatology” This study observed that long-term use of 3% topical minoxidil for androgenetic alopecia resulted in sustained hair regrowth for most patients, although hair counts declined between 12 and 30 months.
19 citations
,
May 2020 in “Cells” This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.
15 citations
,
February 2003 in “British Journal of Dermatology” This study demonstrated that using morphometric and 3D reconstruction software to evaluate scalp biopsies in non-cicatricial alopecias may be feasible and sensitive for detecting subtle follicular changes.