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Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.

JAK inhibitors for alopecia areata are linked to minor side effects like headache and acne, but not to an increased risk of serious adverse events.

Melatonin affects cashmere growth in goats by influencing stem cell and certain signaling pathways.

Guasha changed rat skin appearance and blood vessels temporarily without affecting certain nerve proteins or fiber structure.

Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Pregnancy can cause symptoms similar to rheumatic diseases, making diagnosis difficult, and affects various body systems, requiring careful distinction between normal changes and serious conditions.

Psychotropic drugs can help treat skin conditions affected by mental health, but dermatologists must use them carefully due to side effects and patient concerns.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Painful hair loss in an elderly woman was caused by giant cell arteritis, not just aging.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Clascoterone is safe for the heart, even at high doses.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

Most inconsolable crying in infants is not due to a serious cause, and a detailed check-up is typically enough to find the reason.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.

Prolonged linseed ingestion is safe for rabbits.

A new gene variant in the DSP gene is linked to a unique type of hair loss.

The editor suggests removing "race" and "ethnicity" from dermatology and creating tools to objectively assess skin color and hair texture.

The document explains the genetic causes and characteristics of inherited hair disorders.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Doctors should recognize and treat PCOS early in primary care to manage symptoms and lower risk of other health issues.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Biologics for severe asthma have known side effects, but some new risks need more study.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.