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The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

PLD is an effective and safer alternative for treating breast cancer.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.