108 citations
,
July 2004 in “American Journal of Pathology” This study suggests that nerve growth factor plays a crucial role in the stress-induced termination of hair growth in mice, and its antagonism might offer a therapeutic approach to mitigate stress-related hair loss.
91 citations
,
August 2015 in “Anais Brasileiros De Dermatologia” This review discusses the clinical, epidemiological, and pathophysiological aspects of female pattern hair loss, reporting no new research findings.
75 citations
,
March 2014 in “Journal of Investigative Dermatology” This study found that aging mice experience slower and more fragmented hair cycle waves, but transplanting aged skin to a young host can partially restore hair cycling, implicating extracellular factors.
70 citations
,
April 2016 in “Experimental Dermatology” In this study, oral tofacitinib treatment led to significant hair regrowth and changes in skin and blood biomarkers in a patient with alopecia areata.
68 citations
,
March 1965 in “The BMJ” Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
57 citations
,
March 2018 in “International Journal of Molecular Sciences” This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.
44 citations
,
September 2019 in “The EMBO Journal” This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.
44 citations
,
April 2017 in “Genes & development” This study identified hair shaft progenitors in the matrix that regulate hair growth and pigmentation by creating a niche dependent on stem cell factor, implicating KROX20+ cells in these processes.
34 citations
,
November 2010 in “Development” In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.
28 citations
,
March 2017 in “Endocrinology” In this study, the researchers found that vitamin D and calcium signaling in keratinocytes are essential for normal skin regeneration after wounding, with deficiencies significantly delaying wound closure and re-epithelialization in mice.
24 citations
,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
24 citations
,
May 2013 in “Drug Design Development and Therapy” This pilot study found that a multimodal minoxidil microemulsion with diclofenac and tea tree oil was more effective and safer than minoxidil alone for treating androgenic alopecia over 32 weeks.
9 citations
,
May 1989 in “Journal of the Royal Society of Medicine” An elderly woman's swollen, painful foot was found to be caused by a rare type of bone lymphoma, which improved with radiation treatment.
4 citations
,
December 2020 in “Mammalian genome” This study found that pelage abnormalities in Harlequin mutant mice are linked to severe AIF deficiency and associated with altered expression of genes related to hair structure.
3 citations
,
February 2025 in “Frontiers in Food Science and Technology” This perspective proposes a new classification system for "superfoods" to better align them with environmental and social sustainability goals, emphasizing plant-based sources over animal-based ones due to lower greenhouse gas emissions and deforestation impacts.
1 citations
,
October 2017 in “Circulation” The researchers reported that introduction of SOX9 in ischemic heart tissues is linked to cardiac fibrosis, marking it as a potential target for future therapeutic strategies.
1 citations
,
August 1995 in “Archives of Disease in Childhood” This personal narrative from "Archives of Disease in Childhood" 1995 underscores that empathy, explanation, and reassurance may be more effective than medication for those experiencing delayed puberty and related social challenges; no clinical results are provided.
January 2011 in “Healthcare Informatics Research” This study found that symptoms like dry hair, seborrheic scalps, and certain lifestyle factors correlate with hair loss in patients at hair loss clinics.
58 citations
,
April 2012 in “Journal of the American Academy of Dermatology” Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.
30 citations
,
September 2017 in “Environmental health perspectives” This study found that potential exposure to Corexit™ dispersants during the Deepwater Horizon cleanup was associated with increased respiratory, dermal, and eye irritation symptoms among responders both during the cleanup and up to three years later.
25 citations
,
December 2018 in “Human Molecular Genetics” This study found that the PSEN1-P242LfsX11 mutation in hidradenitis suppurativa influences cytokine and chemokine expression in macrophages, potentially affecting inflammatory responses.
12 citations
,
June 2017 in “Cell Cycle” This study observed that 5% minoxidil topical foam alters gene expression and signaling pathways in the scalp, providing insights into its mechanism of action in men with androgenetic alopecia.
165 citations
,
January 2014 in “Dermatology Research and Practice” This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.
18 citations
,
May 2016 in “Aesthetic Surgery Journal” This study found that body hair transplantation using follicular unit extraction was effective and resulted in high satisfaction among selected patients with limited scalp donor hair.
January 2024 in “Faculty of 1000 Research Ltd” In this study, researchers at Muhimbili National Hospital observed that pediatric cancer patients undergoing chemotherapy frequently experienced adverse drug reactions, such as nausea and vomiting, hair loss, and neutropenia, despite drug prescribing patterns aligning with the essential medicine list.
January 2024 in “Faculty of 1000 Research Ltd” This study found that aesthetic plastic surgeons in Guangdong, China, show strong interest in continuing education, with varied preferences based on the type of hospital they work in.
January 2023 in “Faculty of 1000 Research Ltd” This study found a strong interest among aesthetic plastic surgeons in Guangdong, China, for further training courses, with significant differences in training preferences between private and government hospital surgeons.
January 2022 in “Faculty of 1000 Research Ltd” This study observed that the COVID-19 pandemic influenced patterns of skin and venereal diseases among Iraqi females, with some conditions like hair loss increasing, while others like viral infections decreased.
January 2015 in “Faculty of 1000 Research Ltd” BPH treatment improved with personalized medicine, new drugs, and less invasive surgeries.
January 2023 in “Faculty of 1000 Research Ltd” This study found that hair plucking induced greying in castrated mice, suggesting that decreased androgen levels could play a role in age-related hair greying in humans.