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Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Improving skin barrier and using antifungal treatments can help manage dandruff.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Minoxidil and finasteride effectively treat hair loss.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Some common medications can harm male fertility, but many effects can be reversed.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Fractional laser resurfacing is effective and safe for skin treatment, with benefits like less downtime and a low risk of adverse events.

Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.

Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.

The conclusion is that exogen is a unique hair cycle phase and the new sampling method specifically targets this stage, which may help in future hair loss research.

Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.

Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.

Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.

Iontophoresis improves minoxidil delivery for alopecia treatment.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.