4 citations
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September 2024 in “Development” This study investigated transcription factors in human trophectoderm cells during development, finding that GATA2 and GATA3 are essential for transforming stem cells into induced trophoblast stem cells, which display characteristics similar to placental progenitor cells, offering new methods for modeling placental-associated diseases.
28 citations
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January 2012 in “Case Reports in Medicine” This article discusses Hair-thread Tourniquet Syndrome in children, emphasizing the need for prompt examination and intervention to prevent severe complications, but reports no new clinical results.
2 citations
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February 2024 in “Indian Dermatology Online Journal” This study reports that tofacitinib, a JAK 1/3 inhibitor, showed significant improvement in a patient with co-occurring severe alopecia totalis and lichen planus hypertrophicus, conditions that are typically resistant to treatment.
May 2022 in “European medical journal” This case report highlights a rare instance of gastric trichobezoar, or "Rapunzel syndrome," associated with trichotillomania, characterized by hair accumulation in the stomach of a patient.
May 2022 in “Endocrine practice” This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.
52 citations
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July 2011 in “PubMed” This review discusses the diverse roles of the TRPS1 gene in regulating cartilage, kidney, and hair follicle development, highlighting its functions and interactions, but provides no new experimental results.
4 citations
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May 2019 in “Sultan Qaboos University Medical Journal” Tofacitinib helped regrow hair in a patient with severe hair loss and improved their quality of life without side effects.
November 2013 in “International Journal of Medical and Health Sciences” This review discusses hair tourniquet syndrome, highlighting its potential for delayed diagnosis and the association with maternal telogen effluvium, but reports no new clinical results.
11 citations
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January 2018 in “Acta dermato-venereologica” In this study, oral tofacitinib showed higher efficacy and tolerability in treating refractory alopecia totalis and universalis compared to traditional treatments, achieving a 50% improvement in severity scores for 44.4% of patients over six months, with fewer adverse effects.
February 2021 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that women with telogen effluvium had significantly lower serum copper and zinc levels compared to controls, suggesting these deficiencies may be associated with the condition.
105 citations
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February 2010 in “Endocrinology” This study found that normal human epidermis expresses TSH and may be an indirect target of TSH signaling, with expression regulated by endocrine controls of the hypothalamic-pituitary-thyroid axis.
5 citations
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December 2014 in “Polish Journal of Public Health” This review discusses the mechanisms of zinc transport, its role in human health, and the effects of zinc imbalance, without reporting new results.
February 2025 in “Animals” This study involving 81 yaks found significant correlations between melatonin, dihydrotestosterone, and immunoglobulin levels in blood serum and mineral content in hair, suggesting these factors may jointly influence yak hair growth and immune status, providing a potential non-invasive indicator of overall health.
November 2025 in “ACS Nano” This study reported the development of a pH-responsive microreactor that effectively targets infections by eradicating over 99.9% of MRSA and reprogramming the immune response to promote healing, achieving complete infection clearance and tissue regeneration in a 7-day period.
6 citations
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July 1990 in “The Journal of Pediatrics” A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.
14 citations
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February 2020 in “Scientific reports” This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.
June 2025 in “British Journal of Dermatology” This study found that both tofacitinib and methotrexate effectively reduced hair loss and psychological distress in patients with moderate-to-severe alopecia areata, but tofacitinib showed much greater efficacy. Both treatments had similar safety profiles, with no serious adverse effects reported.
September 2022 in “Journal of the American Academy of Dermatology” This study observed that tofacitinib therapy over about 16 weeks had a positive effect in children with alopecia areata, reducing the SALT index significantly in some patients.
October 2024 in “Endocrinology Insights” In this study, researchers found that both the EU-TIRADS and Bethesda systems exhibited high specificity but suboptimal sensitivity for predicting thyroid nodule malignancy in patients who underwent surgery, with Bethesda system showing particularly high specificity in this postoperative population.
12 citations
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July 1979 in “International Journal of Dermatology” This article reviews the clinical manifestations and contributing factors of acute zinc depletion syndrome, reporting no new results but discussing prevention and treatment strategies.
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that TET2 plays a tumor-suppressive role in preventing squamous cell carcinomas by regulating 5-hydroxymethylcytosine levels, suggesting therapeutic potential for DNA methylation dynamics.
September 2024 in “Quality in Sport” This study provides a comprehensive review of trichotillomania, focusing on its clinical symptoms, etiology, diagnostics, and treatment methods, while also addressing serious complications like trichobezoars and Rapunzel Syndrome.
36 citations
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March 2011 in “Nature Communications” This study found that TSC2-null fibroblast cells from TSC skin hamartomas can induce hair follicle formation and hamartomatous changes in keratinocytes, with active mTOR signaling observable in a mouse xenograft model.
17 citations
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December 2015 in “Bioorganic & Medicinal Chemistry” 3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
139 citations
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November 2016 in “Journal of the American Academy of Dermatology” In this retrospective review, tofacitinib treatment was associated with clinically significant hair regrowth in most adolescent patients with alopecia areata, though limitations suggest further studies are needed to confirm these findings.
26 citations
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September 2023 in “Journal of Allergy and Clinical Immunology” Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
87 citations
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August 1974 in “Journal of Investigative Dermatology” 60 citations
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August 2022 in “ESMO Open” This review discusses managing common and notable adverse events associated with the antibody-drug conjugate trastuzumab deruxtecan in patients with HER2-positive unresectable/metastatic breast cancer and reports no new clinical results.
June 2024 in “Archives of dermatological research” Targeted testing for telogen effluvium patients can save healthcare costs.
November 2025 in “Mendeley Data” This study found that tofacitinib and baricitinib, when administered with unorthodox weight-stratified dosing in pediatric patients with moderate-to-severe AA, showed comparable efficacy and tolerability, though baricitinib's efficacy decreased with non-standard dosing.