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Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Hair loss is significantly linked to lower levels of certain genes in hair follicles.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Sulforaphane from broccoli can help protect skin from sun damage.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Cell aging can be both good and bad for tissue repair.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

XEDAR triggers a specific signaling pathway in cells.

The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Sex steroids affect the MafB gene differently in male and female hamsters.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Testosterone may slow down wound healing and increase inflammation.

Older skin has higher cancer risk due to inflammation and stem cell issues.