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The painting of an 18th-century Sicilian baroness shows she had hair loss, possibly due to ovarian issues, insulin resistance, or a specific type of tumor.

A young girl with high testosterone was thought to have a tumor but actually had PCOS, which was treated with birth control pills.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Acne is not a key diagnostic feature for PCOS, postadolescent men with acne may have insulin resistance, melanoma patients often have few moles, tumor size in CSCC indicates higher risk of serious outcomes, and hidradenitis suppurativa is linked to higher risk of heart problems and death.

A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.

Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.

Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

A man with a rare adrenal cancer showed unusual symptoms and died four months after diagnosis.

Genetic manipulations that extend lifespan in mice may not work as effectively in humans.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Septin4 helps kill colon cancer cells by working with the protein BAX.

Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.

The combination treatment showed a higher response rate but no significant survival benefits.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.