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The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Mutant mice help researchers understand hair growth and related genetic factors.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.

TGF-β2 plays a key role in human hair growth and development.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Prolactin may be important for skin growth and immune function.

Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Thymosin β4 helps improve skin healing and reduce scarring.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.