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RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

SIPHL1 from tomato enhances plants' response to low phosphate levels.

FGF9 from certain T cells helps create new hair follicles during wound healing, which could potentially be used for hair loss treatments.

A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.

FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.

GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.

A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.

The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.

SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

Scientists made a mouse that can be made to lose hair and then grow it back.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

Adding TERT and BMI1 to certain skin cells can improve their ability to create hair follicles in mice.

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.

Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Blocking a specific protein signal can make hair grow on mouse nipples.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Bioluminescence imaging can track hair follicle cells and help study hair regrowth.

Smad2/3-dependent TGF-β signaling increases during wound healing.

Animal models, especially mice, are essential for advancing hair loss research and treatment.