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Transplanted transected hair follicles can survive but grow at unsatisfactory rates and are thinner, suggesting limited potential for unlimited donor hair supply.

Cutting hair follicles into pieces for transplantation results in poor growth and thinner hair, and the technique is more invasive than previously thought.

The recipient site can affect the growth and survival of transplanted hair but not its thickness.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Improving the environment and cell interactions is key for creating human hair in the lab.

Somatostatin may help protect hair follicles from immune attacks.

Partial hair follicle extraction can effectively double the number of hair follicles for transplants, with most surviving and growing normally after a year.

Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.

Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.

Researchers successfully transplanted hair follicles in mice, which survived well and helped in wound healing.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Human hair cells can be used to grow new hair on rat ears, suggesting a possible treatment for hair loss.

Increasing EGR1 levels makes hair root cells grow faster.

Improving dermal papilla cells can help regenerate hair follicles.

The risk of skin tumors becoming malignant depends on the specific skin cell type affected.

Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.

Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

A gene mutation in mice causes permanent hair loss and skin issues.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

Ornithine decarboxylase is crucial for hair growth regulation in mice.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Notch/RBP-J signaling is crucial for proper placement and timing of melanocyte development in hair follicles.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

IGF-1 increases whisker growth in transgenic mice.

DNMT3A is crucial for healthy skin and hair growth.

Increased ornithine decarboxylase makes normally tumor-resistant mice more sensitive to tumors.