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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Androgens can both increase and decrease hair growth in different parts of the body.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Lactate production is important for activating hair growth stem cells.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Fungi-produced compounds can change plant root growth.