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Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Mutant mice help researchers understand hair growth and related genetic factors.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

Inactive hair follicle stem cells help prevent skin cancer.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.

Finasteride helps reduce heart issues and improves heart function.