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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Muscles can make their own androgens, which may help muscle growth.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Using steroids can increase the risk of heart problems.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Researchers had trouble finding enough participants for a trial on DHEA's effects on postmenopausal women's sexual desire.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

New treatments for male hypogonadism are effective and should be personalized.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.