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Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Some common medications can harm male fertility, but many effects can be reversed.

New treatments for male hypogonadism are effective and should be personalized.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Birth control pills increase the risk of blood clots, especially within the first year and with certain types.

Hair loss treatments work better with lifestyle changes.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Menopause affects hair and skin; more research needed for treatment.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.