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Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

FFA's causes may include environmental triggers and genetic factors.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Wnt signaling is crucial for skin wound healing and reducing scars.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

New genes found linked to balding, may help develop future treatments.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Immune cells affect hair growth and could lead to new hair loss treatments.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.