This dissertation found that finasteride reduced prostate volume by 6.3% and total serum PSA by 10.51% in young patients over one year.
In this study, a clear pattern of selective sweep was observed for the SLC24A5 gene, with high linkage disequilibrium and low haplotype diversity, but no clear correlation with UV radiation intensity was found.
This study found that women with postadolescent acne often exhibit symptoms of hyperandrogenism, such as hirsutism and androgenetic alopecia, but have minimal hormone profile abnormalities.
This study observed that long-term laser hair removal in women may alter hair follicle structures and stem cell interactions, with dermal fibrosis potentially influencing hair regrowth prevention.
This case report describes a 14-year-old girl with coeliac disease who presented with severe hypercalcaemia due to a parathyroid adenoma, which resolved after its excision.
This study reviewed and reclassified 37 cases of primary scarring alopecia using histological methods to achieve more accurate diagnoses within subtypes like lupus erythematosus and lichen planopilaris.
September 2009 in “Annales D Endocrinologie” This article reviews the clinical signs, diagnostic approaches, and treatment options for hyperandrogenism in women, focusing on hirsutism and specifies that cyproterone acetate is effective for severe cases, but reports no new clinical results.
January 2007 in “Más dermatología” This review found no clinical studies on hair shaft disorder treatments but reported improvement from minoxidil or oral retinoids in certain conditions, emphasizing gentle hair care and genetic counseling for management.
160 citations
,
January 2017 in “Development” This study found that hypertrophic chondrocytes at the fracture callus border may convert to osteoblasts, influenced by vasculature and pluripotency gene expression.
108 citations
,
January 2003 in “Journal of Cosmetic Dermatology” This summary explains the different types of wrinkles, their causes, and their distinct microanatomical characteristics, noting that each type may respond differently to treatments.
97 citations
,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.
46 citations
,
July 2007 in “Journal of comparative neurology” This study found that Florida manatees have unique types of specialized nerve endings in their vibrissae, which assist in their sensory and manipulative functions in aquatic environments.
32 citations
,
March 2015 in “The Journal of Clinical Endocrinology & Metabolism” In this study, alopecia areata was associated with thyroid autoimmunity but not islet autoimmunity, correlating with specific class II HLA haplotypes linked to various autoimmune diseases.
30 citations
,
April 2017 in “Journal of structural biology” This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.
28 citations
,
July 2015 in “American Journal of Clinical Dermatology” This study found a higher prevalence of metabolic syndrome in patients with lichen planus, especially those with mucosal involvement, which is associated with increased cardiovascular and diabetes risk.
24 citations
,
November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” In this study, mutations in the vitamin D receptor were identified in Brazilian children with rickets and alopecia, leading to impaired receptor activation and reduced 24-hydroxylase expression.
24 citations
,
January 2003 in “Journal of Investigative Dermatology” In this study, a synthetic antagonist of the p75 neurotrophin receptor was found to significantly inhibit hair follicle regression in murine skin cultures, suggesting a potential role in treating hair disorders characterized by premature catagen entry.
23 citations
,
March 2010 in “Actas Dermo-Sifiliográficas” In this study, early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid atherosclerosis compared to controls, suggesting cardiovascular screening might be beneficial for this group.
23 citations
,
April 2004 in “American Journal of Ophthalmology” This case report found that topical bimatoprost usage in a female Hispanic patient with open-angle glaucoma was associated with hypertrichosis and increased pigmentation of vellus hairs on the malar region.
22 citations
,
January 2015 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses the increased use of platelet-rich plasma in dermatology for conditions like skin ulcers and alopecia but reports no new clinical results, emphasizing the need for more scientific evidence to support its benefits.
16 citations
,
August 2007 in “Histopathology” This case report describes a functional adrenocortical oncocytoma that co-secreted testosterone and cortisol.
15 citations
,
May 2010 in “Actas Dermo-Sifiliográficas” This study found that men with early-onset androgenetic alopecia had a higher prevalence of metabolic syndrome and carotid atheromatous plaques than control subjects, suggesting a need for cardiovascular screening in this group.
15 citations
,
March 2004 in “American Journal of Ophthalmology” This case report found that topical bimatoprost in a female Hispanic patient with glaucoma led to increased hair growth and pigmentation in the malar region, which resolved after discontinuing use and epilation.
12 citations
,
December 2018 in “Clinical Ophthalmology” This review summarizes clinical trials and comparative studies showing that latanoprostene bunod 0.024% is effective and safe for reducing intraocular pressure in patients with open-angle glaucoma or ocular hypertension, detailing its mechanism and side effects while considering its therapeutic role.
12 citations
,
March 2010 in “Revista iberoamericana de micología” This case report describes a Persian cat with dermatophytic pseudomycetoma that initially responded to griseofulvin treatment and surgical excision, but the condition relapsed, ultimately leading to the cat's death.
11 citations
,
May 2009 in “Actas Dermo-Sifiliográficas” This review discusses various therapeutic options for alopecia areata and reports no new clinical results; treatments may manage symptoms but do not cure the condition.
10 citations
,
November 2021 in “Revista médica de Chile” This review discusses the clinical guidelines for hidradenitis suppurativa, detailing its definition, impacts, and treatments, and includes a proposed therapeutic approach algorithm, but reports no new clinical findings.
10 citations
,
April 2018 in “Actas Dermo-Sifiliográficas” This study describes the prescribing habits of Spanish dermatologists, highlighting that topical minoxidil and oral finasteride are the most common treatments for male AGA and postmenopausal female AGA.
9 citations
,
August 2014 in “European journal of ophthalmology” This study found that PGF 2α receptors were predominantly present in the inner root sheath of the bulb and stem of human eyelashes during the anagen phase.
8 citations
,
August 2016 in “Acta dermato-venereologica” Timolol eye-drops can cause hair loss.