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Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

People who are more materialistic often expect life changes from buying things, leading to more debt and credit misuse.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Some systemic treatments work for nail psoriasis but can have serious side effects.

High-frequency ultrasonography is a useful but underused tool in dermatology for assessing skin cancers, monitoring diseases, and evaluating treatments.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Facial rejuvenation surgery has evolved to yield natural results with low complication rates, and more men and older patients are choosing this surgery.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

The debate on direct-to-consumer pharmaceutical ads continues, with consumers finding them educational and doctors concerned about their impact on patient relationships and medication understanding.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Social housing is a system for those with limited financial resources, needing subsidies and an allocation system, with Germany fitting this criteria.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.