37 citations,
November 2003 in “Veterinary pathology” Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.
30 citations,
December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
30 citations,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
30 citations,
September 2017 in “Clinics in Dermatology” Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
30 citations,
May 2016 in “Expert Opinion on Biological Therapy” New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
29 citations,
March 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Older age at onset of alopecia areata leads to less severe and shorter episodes, with most patients experiencing significant hair regrowth.
29 citations,
January 2011 in “Journal of Obstetrics and Gynaecology” Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
28 citations,
November 2017 in “Skin appendage disorders” The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.
27 citations,
April 2018 in “Journal of autoimmunity” iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.
27 citations,
May 2007 in “Archives of dermatological research” Diphencyprone treatment increases CD8 lymphocytes in the scalp, which is associated with hair regrowth in alopecia areata patients.
27 citations,
January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
25 citations,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
24 citations,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
23 citations,
October 2005 in “Journal of The American Academy of Dermatology” Two transplant patients on cyclosporine unexpectedly developed hair loss.
23 citations,
January 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
22 citations,
August 2011 in “Endocrine Practice” Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
21 citations,
December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
20 citations,
July 2009 in “Journal of Pediatric and Adolescent Gynecology” Quick treatment of hair disorders in teenage girls is important because of the emotional effects.
18 citations,
June 2010 in “Current medicinal chemistry” Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.
17 citations,
October 2012 in “Dermatologic clinics” Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.
16 citations,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
15 citations,
April 2003 in “Journal of dermatology” Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.
15 citations,
September 1984 in “Veterinary Clinics of North America: Small Animal Practice” The document explains various skin conditions in cats and how to diagnose and treat them.
14 citations,
May 2011 in “Facial Plastic Surgery Clinics of North America” Laser hair removal is effective for dark hair but needs improvement for nonpigmented or fine hairs.
14 citations,
January 1985 in “International Journal of Dermatology” The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.
14 citations,
September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
14 citations,
March 2010 in “Gynecological endocrinology” New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
13 citations,
September 2016 in “Cosmetics” Hair care cosmetics affect hair health; know products, ingredients, and procedures.
13 citations,
July 2011 in “Photomedicine and laser surgery” Coloring white hair before IPL treatment effectively helps remove it.